ENHANCE: Development and evaluation of a targeted, integrated, coherent and people-centred approach to the management of multimorbidity in South African primary healthcare
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UKZN LEAD:
Professor Inge Petersen -
WORK PACKAGE FOUR CO-LEADS:
Professor Inge Petersen, Associate Professor Andre Van Rensburg, Professor Mosa Moshabela -
CRH STAFF ON THE TEAM:
Dr Tasneem Kathree, Associate Professor Zamasomi Luvuno, Professor Arvin Bhana, Londiwe Mthethwa-Bhengu, Sanah Bucibo, One Selohilwe, Gcina Radebe,
Associate Professor Bernhard Gaede -
TIMELINE:
Sept 2021 - August 2025 -
BUDGET:
£1 200 000 -
FUNDERS:
UK NIHR (Right) -
COLLABORATORS:
Kings College London; University of Cape Town; KwaZulu-Natal Department of Health; Western Cape Department of Health
Description:
Overall aim: To co-produce and evaluate a scalable health system intervention and implementation strategy for improved management of commonest configurations of multiple long-term conditions (MLTCs) in SA that balances clinical evidence, local policies, patient and community preferences and health system constraints. The study is in collaboration with Kings College London and the Knowledge Translation unit at the University of Cape Town. It comprises six work packages, with UKZN leading WP4, which entails formative work designed to inform the implementation strategy for the intervention. The intervention comprises strengthened health promotion materials in the waiting rooms, an integrated set of clinical guidelines for use by Professional nurses/doctors for the commonest configurations of MLTC, and outreach to households by community health worker teams to provide support using a patient held diary. The intervention is being tested through a cluster randomized control trial in KwaZulu-Natal and the Western Cape province, with the UKZN team leading the trial in KwaZulu-Natal.
PhD study are nested within ENHANCE:
David Zezai: Understanding how to strengthen health systems for people-centred care of people with Multiple Long-Term Conditions – Multimorbidity at Primary Health Care level in South Africa.
Current Highlights/Updates:
The trial is currently underway with baseline data collection completed, and 6-month follow-ups in progress.
Publications:
Johnson LF, Kassanjee R, Folb N, et al. A model-based approach to estimating the prevalence of disease combinations in South Africa. BMJ Global Health 2024;9:e013376.
