African HIV, Infectious Diseases and Global Health Implementation Research Institute (Afri-HIGH IRI)

The Issue

Despite major scientific advances, the translation of research evidence into effective health interventions remains limited—particularly in resource-constrained settings in Africa. Strengthening capacity in implementation science (IS) is essential to bridge the gap between evidence and real-world practice for HIV, infectious diseases, and other global health challenges.

The Intervention

The African HIV, Infectious Diseases and Global Health Implementation Research Institute (Afri-HIGH IRI) is a mentored training programme jointly hosted by the University of KwaZulu-Natal (UKZN) and the University of Zambia (UNZA), in collaboration with Washington University in St. Louis (WUSTL). Modelled on the successful HIGH IRI programme, Afri-HIGH IRI builds a network of early- to mid-career African researchers through a two-year curriculum combining intensive training, mentorship, and experiential learning focused on IS methods and application.

The Impact

Afri-HIGH IRI is cultivating a new generation of African implementation scientists equipped to close the research-to-practice gap in HIV and infectious diseases. The inaugural 2025 cohort includes 17 fellows from across Africa, representing diverse disciplines and countries. The programme strengthens local research leadership, fosters regional collaboration, and contributes to more equitable, evidence-based health systems across the continent.

Project Keywords

Africa
Capacity building
Implementation scientists